Analysis Note

ControlRat brain tissue.

Application

Anti-Neurogenin-3 Antibody, a.a. 80-93 of mouse Neurogenin-3. detects level of Neurogenin-3 & has been published & validated for use in IH.

Immunohistochemistry: 1:200-1:1,000.
Immunocytochemistry: Cat. # AB5684 detects Neurogenin-3 in PC12 cells at 1:500 dilution.
Not recommended for Western blot

Research CategoryNeuroscience

Research Sub CategoryDevelopmental NeuroscienceNeuronal & Glial Markers

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. The neurogenins (ngns) make up one of these atonal-related gene families. In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (Mash1 Is Essential for Noradrenergic Differentiation). Neurogenin-3 promotes pancreatic development.

Immunogen

Epitope: a.a. 80-93 of mouse Neurogenin 3.

Synthetic peptide, amino acids 80-93 of mouse Neurogenin 3.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

Specificity

Recognizes Neurogenin 3 (MATH4b), a Helix-loop-helix class of transcription factor.

Storage and Stability

Stable for 1 year at -20°C from date of receipt.

Target description

~ 23 kDa